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俞家华


作者: 来源:放射医学与防护学院 日期:2017-11-23 2017-11-23 人气:2608 

俞家华,副教授,硕士生导师

电话:0512-65880065

传真:0512-65884380

电子邮箱:yujiahua@suda.edu.cn

通讯地址:苏州市工业园区仁爱路199号402-2319,215123

个人简介

俞家华,2004年毕业于苏州大学放射医学专业,获得医学学士学位,后赴韩国国立全北大学攻读研究生,于2010年获得医学博士学位。2011年至今在苏州大学医学部放射医学与防护学院放射生物学教研室任教,主持国家自然科学青年基金一项,江苏省高校自然科学研究面上项目一项,以通讯作者和第一作者发表SCI期刊论文12篇。

研究方向

放射性肺损伤机制和防治

肿瘤辐射增敏

电离辐射诱导DNA损伤机制

科研项目

1. 国家自然科学基金青年项目,脂肪干细胞治疗放射性肺损伤及其机制研究(81202149),2013/01-2015/12,负责人。

2. 江苏省高校自然科学研究面上项目,IL-6介导的STAT3通路参与放射性肺炎发病的机制研究(13KJB310016),2013/08-2015/12,负责人。

代表性论著

1. Jie Du, Jun Shang, Fei Chen, Shuyu Zhang, Narui Yin, Ting Xie, Haowen Zhang, Jiahua Yu*, Fenju Liu*, A CRISPR/Cas9-based screening for non-homologous end joining inhibitors reveals ouabain and penfluridol as radiosensitizers. Mol Cancer Ther. 2017, doi: 10.1158/1535-7163.MCT-17-0090.

2. Song Hua#, Jiahua Yu#, Jun Shang, Haowen Zhang, Jie Du, Yushuo Zhang, Fei Chen, Yuan Zhou, Fenju Liu*. Effective tumor-targeted delivery of etoposide using chitosan nanoparticles conjugated with folic acid and sulfobetaine methacrylate, RSC Advances 2016, 6(94): 91192-91200

3. Jiahua Yu*, Xiaopeng Yuan, Yang Liu, Kaishuo Zhang, Jie Wang, Haowen Zhang, Fenju Liu*. Delayed administration of WP1066, an STAT3 inhibitor, ameliorates radiation-induced lung injury in mice, Lung 2016, 194(1): 67-74.

4. Xiaopeng Yuan#, Jie Du#, Song Hua, Haowen Zhang, Cheng Gu, Jie Wang, Lei Yang, Jianfeng Huang, Jiahua Yu*, Fenju Liu*. Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells. Experimental Cell Research, 2015, 330(2): 267-276.

5. Jie Wang, Xiaopeng Yuan, Cheng Gu, Jianfeng Huang, Jiahua Yu*, Fenju Liu*. Pretreatment of gelsolin antibody aggravates radiation-induced lung injury in mice. Nuclear Science and Techniques 2014, 25,020301.

6. Jiahua Yu, Sun-O Ka, Kang-Beom Kwon, Sang-Myeong Lee, Jin-Woo Park, and Byung-Hyun Park*. Overexpression of the small GTPase Arl4d suppresses adipogenesis. Int J Mol Med 2011; 28(5):793-798.

7. Ikjae Lee#, Jiahua Yu#, Yesie Yoon, Hyo Jin Gim, Sang-Myeong Lee, Jin-Woo Park, Roak Jeon, and Byung-Hyun Park. [5-(3-Indol-1-ylpropoxy)-1H-indol-3-yl] acetic acid enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells. International Journal of Pharmacology 2011; 7(5):647-652.

8. Jiahua Yu, Hwa-Suk Lee, Sang-Myeong Lee, Hee-Chul Yu, Woo Sung Moon, Myoung Ja Chung, Jin-Woo Park, and Byung-Hyun Park*. Aggravation of post-ischemic liver injury by overexpression of A20, an NF-κB suppressor. J Hepatol 2011; 55(2): 328-336.

9. Kuichang Yuan#, Jiahua Yu#, Amin Shah, Shan Gao, Sun Young Kim, Sung Zoo Kim, Byung-Hyun Park, and Suhn Hee Kim. Leptin reduces plasma ANP levels via nitric oxide dependent mechanism. Am J Physiol Regul Integr Comp Physiol 2010; 298(4): R1007-R1016.

10. Jiahua Yu, Kang-Beom Kwon, Jin-Woo Park, Han-Jung Chae, and Byung-Hyun Park. Bax inhibitor-1 overexpression reduces the suppressive effect of calcium mobilizing agent on adipogenesis. Int J Biochem Cell Biol 2009; 41(8-9):1739-1745.

11. Jiahua Yu, Hee-Chul Yu, Kyung-Ah Kim, Kang-Beom Kwon, Jin-Woo Park, Sung-Zoo Kim, Suhn Hee Kim, and Byung-Hyun Park. Differences in the amount of lipolysis induced by atrial natriuretic peptide in small and large adipocytes. J Pept Sci 2008; 14(8): 972-977.

12. Jiahua Yu, Yeon Jun Jeong, Kang-Beom Kwon, Sung-Zoo Kim, Suhn Hee Kim, Jin-Woo Park, Hee-Chul Yu, and Byung-Hyun Park. A comparison of the lipolytic activity of different natriuretic peptides on human adipocytes. Int J Pept Res Ther 2008; 14: 167-172.

授权发明专利

俞家华,刘芬菊,袁小鹏,顾成,王洁,杨磊,一种检测间充质干细胞分布的方法,2015.02.18,中国,ZL201310189450.5

课程教学及招生信息

课程教学及招生信息

放射生物学(研究生,本科生课程)