崔凤梅，教授、硕士生导师

电话：0512-65880052

传真：0512-65884380

电子邮箱：cuifengmei@suda.edu.cn

通讯地址：苏州工业园区仁爱路199号, 邮编215123

个人简介：

    1998年原苏州医学院放射医学本科毕业留校后一直工作至今。先后获得放射医学硕士和博士学位。2006年和2014年分别赴美国乔治敦大学和UAB进行访学和工作。现任中国毒理学会放射毒理专业委员会副秘书长、江苏省毒理学会副秘书长、中华预防医学会放射卫生专委会青年委员会副主委、医学参考报放射防护频道编委。多年来，从事放射毒理学、放射卫生与防护、辐射损伤修复与辐射防护药物等方面的教学和科研。参与《放射卫生与防护》、《核事故医学应急》、《放射毒理学》、《同位素示踪学》、《核与辐射安全漫谈》、《身边的电离辐射》等多门课程的授课。先后承担4项国家自然科学基金和1项国家重点项目，参与了国家自然基金重大国际合作项目、国防科工局“十三五”核能开发科研第二批专项、国家自然科学基金重点项目等的研究。发表论文20余篇。获得1项发明专利。编写《自由基毒理学》和《放射毒理学》书籍。

研究方向：

放射毒理学, 放射损伤与防护

科研项目：

国自然, 氚水辐射损伤后P53/miR-34a/myc通路参与的调控机制，81172706, 2011

近五年发表论文：


  1. Wang KZ, Sun L, Xiong KH, Chen WB, Wang YY, Bian HH, Cui FM(co-corresponding)*, Liu YL. Monitoring of Tritium Internal Exposure Doses of Heavy-Water Reactor Workers in Third Qinshan Nuclear Power Plant. Dose Response. 2019 Nov 22;17(4):1559325819890498. doi: 10.1177/1559325819890498.

  2. Qiu Chen#, Ya-Nan Zeng#, Ke Zhang#, Ying Zhao, Yong-You Wu, Gen Li, Hui-Ying Cheng, Meng Zhang, Feng Lai, Jin-Bing Wang*, Feng-Mei Cui(co-corresponding)*. Polydatin Increases Radiosensitivity by Inducing Apoptosis of Stem Cells in Colorectal Cancer. Int J Biol Sci 2019; 15(2):430-440. doi:10.7150/ijbs.27050

  3. Cui F#, Ma N#, Han X#, Chen N, Xi Y, Yuan W, Xu Y, Han J, Xu X, Tu Y. Effects of 60Co γ Irradiation on the Reproductive Function of Caenorhabditis elegans. Dose Response. 2019; 17(1):1559325818820981. doi: 10.1177/1559325818820981.

  4. Liu X, Chen Q, Ding X, Zhao Y, Zhang K, Yu P, Cui F(co-corresponding), Xue B. X-ray-induced reproductive dysfunction and differentially expressed piRNAs in male mice. Hum Exp Toxicol. 2018; 38(5) 533–546

  5. Zuo X, Chen Q, Li H, Zhang K, Wang K, Tu Y, Hu M, Cui F(co-corresponding), Liu Y. Effects of Chahuangjing on Decorporation and Radiation Protection Against Tritiated Water. Dose Response. 2018 Nov 25;16(4):1559325818810650. doi: 10.1177/1559325818810650.

  6. Li Li, Ke Zhang, Ji Zhang, Ya-Nan Zeng, Feng Lai, Gen Li, Na Ma, Ming-Jiang Hu, Feng-Mei Cui(co-corresponding), Qiu Chen. Protective effect of polydatin on radiation-induced injury of intestinal epithelial and endothelial cells. Bioscience Reports Nov 14, 2018; 38 (6) BSR20180868; DOI: 10.1042/BSR20180868

  7. Feng Mei Cui, Xiu Jin Sun, Cheng Cheng Huang, Qiu Chen, Yong Ming He, Shi Meng Zhang, Hua Guan, Man Song, Ping Kun Zhou*, Jun Hou*. Inhibition of c-Myc expression accounts for an increase in the number of multinucleated cells in human cervical epithelial cells.Oncol Lett. 2017; 14(3): 2878–2886.

  8. Shang Cai, Geng-Sheng Shi, Hui-Ying Cheng, Ya-Nan Zeng, Gen Li, Meng Zhang, Man Song, Ping-Kun Zhou, Ye Tian, Feng-Mei Cui*, Qiu Chen*. Exosomal miR-7 Mediates Bystander Autophagy in Lung after Focal Brain Irradiation in Mice. Int J Biol Sci. 2017; 13(10): 1287–1296.

  9. Cui F, Hou J, Huang C, Sun X, Zeng Y, Cheng H, Wang H, Li C*. C-Myc regulates radiation-induced G2/M cell cycle arrest and cell death in human cervical cancer cells. J Obstet Gynaecol Res. 2017; 43(4): 729-735. doi: 10.1111/jog.13261.

  10. Li G, Wu A, Qi D, Cui F(co-first), Zeng Y, Xie F, Wu H, Gu Y, Chen Q, Zhang X. Differential effects of peptidoglycan on colorectal tumors and intestinal tissue post-pelvic radiotherapy. Oncotarget. 2016; 7(46):75685-75697. doi: 10.18632/oncotarget.12353.

  11. Wang YS, Chen J, Cui F(co-first), Wang H, Wang S, Hang W, Zeng Q, Quan CS, Zhai YX, Wang JW, Shen XF, Jian YP, Zhao RX, Werle KD, Cui R, Liang J, Li YL, Xu ZX. LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors. Oncotarget. 2016 Nov 8;7(45):73389-73401. doi: 10.18632/oncotarget.12334.

  12. Cui FM, Liu L, Zheng LL, Bao GL, Tu Y, Sun L, Zhu W, Cao JP, Zhou PK, Chen Q, He YM. The Role of miR-34a in Tritiated Water Toxicity in Human Umbilical Vein Endothelial Cells. Dose Response. 2016 30; 14(2):1-7. doi: 10.1177/1559325816638585.

  13. Cui F, Fan R, Chen Q, He Y, Song M, Shang Z, Zhang S, Zhu W, Cao J, Guan H, Zhou PK. The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity. Mol Cell Biochem. 2015; 406(1-2):43-51. doi: 10.1007/s11010-015-2422-2. Epub 2015 Jun 7.


课程教学及招生信息:

放射毒理学（本科生、研究生课程）