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朱然


作者: 来源:放射医学与防护学院 日期:2017-12-06 2017-12-06 人气:317 

朱然,副教授,硕士生导师

电话:0512-65880067

传真:0512-65884380

电子邮箱:zhuran@suda.edu.cn

通讯地址:苏州市工业园区仁爱路199号402-2313215123

个人简介

朱然,女,博士,苏州大学放射医学与防护学院副教授,硕导,一直从事核药学和基础核医学的研究工作,近两年来,开展了核素标记的纳米材料针对肿瘤诊疗一体化的研究,致力于放射性标记化合物在生物医药中的应用研究。

工作经历

1997/09 2016/11  苏州大学,放射医学与防护学院

2012               新加坡国立大学附属医院(国际原子能机构培训项目)

2015              德国明斯特大学生物物理研究所(江苏省放射医学协同创新项目)

课题:

1.主持国家自然科学基金项目1项:BTG1调控乳腺组织电离辐射敏感性机制的研究,项目号81502758

2.主持苏州市科技项目1项:BTG1调控电离辐射致乳腺肿瘤DNA损伤修复机制的研究,项目号SYS201417。

最近5年主要学术论文:

1. Li Wei , Shi xingpeng, Xuyan, Wan jianmei , Ran zhu?  Wei shaohua?.Tamoxifen promotes apoptosis and inhibits invasion of estrogen-positive breast cancer MCF-7 cell, Molecular Medicine Reports,2017,16,478-484

2. Wenwen Zhu, ziliang Dong, Tingting Fu, Jingjing Liu, Qian Chen, Yonggang Li, Ran zhu*, Ligeng Xu*, Zhuang Liu*.

Modulation of Hypoxia in Solid Tumor Microenvironment with MnO2 Nanoparticles to Enhance Photodynamic TherapyAdvanced Functional Materials26,5490-5498

3. RAN ZHU, WEI LI, YAN XU, JIANMEI WAN and ZENGLI ZHANG .

Upregulation of BTG1 enhances the radiation sensitivity of human breast cancer in vitro and in vivo Cancer Biother Radiopharm. ONCOLOGY REPORTS 34: 3017-3024, 2015.

4. Ruirui Qiao*, Ran Zhu*, and Mingyuan Gao.

Imaging Tumor Metastases with Molecular Probes. Current Pharmaceutical Design, 2015, 21, 6260-6264

5. Yang C*, Zhu R*, Wan J, Jiang B, Zhou D, Song M, Liu F*.

Biological effects of irradiating hepatocellular carcinoma cells by internal exposure with (125)i-labeled 5-iodo-2'-deoxyuridine-chitosan drug loading nanoparticles. Cancer Biother Radiopharm., 2014;29(9):395-402.

6. Li W, Zou ST, Zhu R, Wan JM, Wu,HR*

B-cell translocation 1 gene inhibits cellular metastasis-associated behavior in breast cancer. Mol. Med. Rep., 2014; 9(6):2374-80.

7. Wan J, Zou S, Hu M, Zhu R, Xu J, Jiao Y, Fan S*

Thoc1 inhibits cell growth via induction of cell cycle arrest and apoptosis in lung cancer cells.

Mol. Med. Rep., 2014; 9(6): 2321-7.

8. Zhu R, Zou ST, Wan JM, Li W, Li XL, Zhu W*

BTG1 inhibits breast cancer cell growth through induction of cell cycle arrest and apoptosis

Oncol. Rep., 2013; 30(5): 2137-44.

9. Xu Y, Zou ST, Zhu R, Li W, Gu CW, Wei SH, Xie JM, Wu HR*.

Inhibition of proliferation of estrogen receptor positive MCF 7 human breast cancer cells by tamoxifen through c Jun transcription factors.Mol. Med. Rep., 2013; 7(4):1283-7.

10. Zhai X, Yang Y, Wan J, Zhu R, Wu Y*

Inhibition of LDH-A by oxamate induces G2/M arrest, apoptosis and increases radiosensitivity in nasopharyngeal carcinoma cells. Oncol. Rep., 2013; 30(6): 2983-91.

奖项:

     1.2016年获得卫生部科技进步三等奖1项(排名第3

1.2015年获得苏州市科技进步二等奖1项(排名第5

2.2010年获得苏州市科技进步三等奖1项(排名第5