周如鸿 特聘教授

日期:2016-7-5 12:43:17 人气:141 

周如鸿,特聘教授

苏州大学放射医学及交叉学科研究院特聘教授,博士生导师,中组部千人计划入选者(2015年),美国科学促进会会士  (AAAS  Fellow),美国物理学会会士 (APS Fellow)。于1988年获浙江大学物理学学士学位,1990年固体物理硕士学位,后留校在浙江大学物理系担任助教,讲师。1993年赴美留学,于1997年获得美国哥伦比亚大学化学博士学位。2000年加盟IBM Watson研究中心担任副研究员,研究员,杰出研究员;并于2002年开始在哥伦比亚大学化学系担任兼职助理教授,兼职教授,讲授《生物物理化学》和《统计力学》等课程。周教授长期从事生物物理,蛋白质科学,与纳米化学等交叉领域的科学研究,拥有或已申请20余项国际专利,在权威学术刊物发表论文160余篇 (其中ScienceNatureNature子刊和PNAS 17),总引用9000余次。应邀在世界各地大学、研究机构和国际学术会议上做邀请报告 150余次。其研究工作多次在国际著名期刊和网站报道。曾获全美化学学会计算化学奖 (ACS DEC Award)IBM杰出科技贡献奖 (IBM技术类最高奖,200520082013)IBM杰出创新奖 (2012)2009年以IBM蓝色基因组主要成员之一荣获奥巴马总统颁发的美国国家技术奖章(National Medal on Technology)。周如鸿教授是《Current Physical Chemistry》主编(Editor-in-Chief),(NatureScientificReports编辑(Editor),《Nanoscale》特邀客座主编,也是《Molecular Simulation》等六家国际期刊的编委。周如鸿教授同时担任美国分子科学领域顶尖的Telluride科学研究中心董事会的董事(Board of Directors),和美国芝加哥大学多尺度科学中心的科学顾问(Scientific Advisory Board)。周如鸿教授于2011年当选AAAS Fellow APS Fellow,并于2012年入选IBM全球八大研究院“将对IBM,对世界,可能产生最重大影响”的五名科学家之一。

代表性论著:

1.P. Liu, X. Huang, R. H. Zhou and B. J. Berne, Observation of a Dewetting Transition in the Collapse of the Melittin Tetramer, Nature, 437, 159-162, 2005

2.R. H. Zhou, X. Huang, C. Margulius and B. J. Berne, Hydrophobic Collapse in Multi-domain Protein Folding, Science, 305, 1605-1609, 2004

3.Y. Tu, M. Lv, P. Xiu, T. Huynh, M. Zhang, M. Castelli, Z. R. Liu, Q. Huang, C. H. Fan, H. P. Fang, and R. H. Zhou, Destructive Extraction of Phospholipids from E. Coli Membrane by a Graphene Nanosheet, Nature Nanotech. 8, 594-601, 2013

4.Michael C. Baxa, Wookyung Yu, Aashish N. Adhikari, Liang Ge, Zhen Xia, R. H. Zhou, Karl F. Freed, Tobin R. Sosnick, Even with non-native interactions, the updated folding transition states of the homologs Protein G & L are extensive and similar, Proc. Natl. Acad. Sci. 112, 8302-8307, 2015

5.Deyi An, Jiguo Su, Jeffrey K. Weber, Xueyun Gao, R. H. Zhou*, Jingyuan Li*, A peptide-coated gold nanocluster exhibits unique behavior in protein activity inhibition, J. Am. Chem. Soc. 137, 8412-8418, 2015

6.Guillaume Stirnemann, Seung-Gu Kang, R. H. Zhou, and B. J. Berne, How Force Unfolding Differs from Chemical Denaturation, Proc. Natl. Acad. Sci. 111, 3413-3418, 2014

7.B. Dai, S. G. Kang, T. Huynh, H. Z. Lei, M. Castelli, J. Hu, Y. Zhang and R. H. Zhou, Salts Drive Controllable Multi-Layered Upright Assembly of Amyloid-like Peptides at Mica/Water Interface, Proc. Natl. Acad. Sci. 110, 8543-8548, 2013

8.S. G. Kang, T. Huynh, Z. Xia, Y. Zhang, H. P. Fang, G. H. Wei and R. H. Zhou, Hydrophobic Interaction Drives Surface-Assisted Epitaxial Assembly of Amyloid-like Peptides, J. Am. Chem. Soc. 135, 3150-3157, 2013

9.P. Das, D. Kapoor, K. T. Halloran, R. H. Zhou, and C. R. Matthews, Interplay between Drying and Stability of a TIM Barrel Protein: A Combined Simulation-Experimental Study, J. Am. Chem. Soc. 135, 1882-1890, 2013

10.S. G. Kang, G. Q. Zhou, P. Yang, Y. Liu, B. Y. Sun, T. Huynh, H. Meng, L. Zhao, G. M. Xing, C. Y. Chen, Y. L. Zhao, R. H. Zhou, Molecular Mechanism of Pancreatic Tumor Metastases Inhibition by Metallofullerenol Gd@C82(OH)22: Implication for de novo Design of Nanomedicine, Proc. Natl. Acad. Sci., 109, 15431-15436, 2012 (featured article)

11.L. Cong, R. H. Zhou, Y. C. Kuo, M. Cunniff, and F. Zhang, Comprehensive Interrogation of Natural TALE DNA Binding Modules and Transcriptional Repressor Domains, Nature Commun. 3, 968, 2012

12.Z. Xia, P. Das, E. I. Shakhnovich, and R. H. Zhou, Collapse of Unfolded Proteins in a Mixture of Denaturants, J. Am. Chem. Soc. 134, 18266-18274, 2012

13.P. Das, J. A. King, and R. H. Zhou, Aggregation of Partially Folded gamma-Crystallin Associated with Human Cataracts via Domain Swapping at the C-terminal beta-strands, Proc. Natl. Acad. Sci. 108, 10514-10519, 2011 (featured article)

14.C. Ge, J. F. Du, L. Zhao, L. Wang, Y. Liu, D. H. Li, Y. Yang, R. H. Zhou, Y. L. Zhao, Z. F. Chai, C. Y. Chen, Binding of human serum proteins on single-wall carbon nanotubes reduces cytotoxicity, Proc. Natl. Acad. Sci, 108, 16968-16973, 2011 (featured article)

15.Y. Tu, P. Xiu, R. Wan, J. Hu, R. H. Zhou and H. Fang, Water-mediated signal multiplication with Y-shaped carbon nanotubes, Proc. Natl. Acad. Sci. 106, 18120-18124, 2009

16.R. Zangi, R. H. Zhou, and B. J. Berne, Urea’s Action on Hydrophobic Interactions, J. Am. Chem. Soc. 131, 1535-1541, 2009

17.L. Hua, R. H. Zhou, D. Thirumalai, B. J. Berne, Urea denaturation by stronger dispersion interactions with proteins than water implies a 2-stage unfolding, Proc. Natl. Acad. Sci., 105, 16928-16933, 2008

18.M. G. Krone, L. Hua, P. Soto, R. H. Zhou, B. J. Berne, and J-E. Shea, Role of Water in Mediating the Assembly of Alzheimer Amyloid-beta Abeta16-22 Protofilaments, J. Am. Chem. Soc. 130, 11066-11072, 2008

19.J. Li, X. Gong, H. Lu, D. Li, H. Fang and R. H. Zhou, Electrostatic Gating of a Nanometer Water Channel, Proc. Natl. Acad. Sci., 104, 3687-3692, 2007

20.X. Li, J. Li, M. Eleftheriou and R. H. Zhou, Hydration and Dewetting near Fluoronated Superhydrophobic Plates, J. Am. Chem. Soc. 128, 12439-12447, 2006

21.M. Eleftheriou, R. Germain, A. Royyuru and R. H. Zhou, Thermal denaturing of mutant lysozyme with both OPLSAA and CHARMM force fields, J. Am. Chem. Soc. 128, 13388-13395, 2006

22.R. H. Zhou, M. Eleftheriou, A. K. Royyuru, B. J. Berne, Destruction of long-range interactions by a single mutation in lysozyme, Proc. Natl. Acad. Sci., 104, 5824-5829, 2007

23.R. H. Zhou, Trp-cage: Folding Free Energy Landscape in Explicit Water, Proc. Natl. Acad. Sci.,100, 13280-13285, 2003

24.R. H. Zhou and B. J. Berne, Can a continuum solvent model reproduce the free energy landscape of a beta-hairpin folding in water?, Proc. Natl. Acad. Sci. 99, 12777-12782, 2002

25.R. H. Zhou, B. J. Berne and R. Germain, Free energy landscape of a beta-hairpin folding in explicit water, Proc. Natl. Acad. Sci. 98, 14931-14936, 2001


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