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田欣


作者: 来源:放射医学与防护学院 日期:2019-05-13 2019-05-13 人气:580 

田欣,副教授

电子邮箱:xtian@suda.edu.cn
通讯地址:苏州工业园区仁爱路199, 邮编215123

个人简历:

田欣苏州大学医学部放射医学与防护学院副教授2013年毕业于中国科学院国家纳米科学中心,获博士学位,师从赵宇亮院士和聂广军研究20159-20169美国食品药品监督管理局访问研究。20138月进入苏州大学放射医学与防护学院。迄今为止共发表SCI学术论文30余篇,授权国际专利1项,中国专利1项。

  

研究方向:

结合医学、生物学和化学等交叉学科的方法,研究在纳米尺度上新型材料与生物体的相互作用等纳米生物医学中的基本问题。主要包括:

1.新型纳米材料的生物安全性评价研究;

2.新型纳米材料在放射医学中的应用研究;

3.  细胞膜囊泡系统及其在纳米材料生物效应中的分子机制。

  

科研项目:

        1. 2015.01-2017.12  外泌体(exosome)介导纳米颗粒外排及其在肿瘤细胞耐药性产生机制中的研究,国家自然科学基金青年基金,23万,主持

        2.2015.07-2018.06  树枝状Au-Pt纳米复合材料作为肿瘤放疗增敏剂的研究,中国博士后面上基金项目,5万,主持

代表性论著:

    1.X Tian,# Y Sun,# S Fan, MD Boudreau, C Chen, C Ge*, JJ Yin. Photogenerated Charge Carriers in Molybdenum Disulfide Quantum Dots with Enhanced Antibacterial Activity. ACS Applied Materials & Interfaces, 2019, 11, 4858−4866.      IF: 8.097

    2.X Tian,# S Liu,# J Zhu, Z Qian, L Bai, Y Pan*. Biofunctional Magnetic Hybrid Nanomaterials for Theranostic Applications. Nanotechnology, 2019, 30, 032002.     IF: 3.404

    3.C Li,# Y Sun,# X Li, # S Fan,* Y Liu, X Jiang, MD Boudreau, Y Pan,* X Tian*. Bactericidal Effects and Accelerated Wound Healing using Tb4O7 Nanoparticles with Intrinsic Oxidase-Like Activity. Journal of Nanobiotechnology, 2019, 17, 54.      IF: 5.294

    4.X Tian, X Jiang, C Welch, T Croley, T Wong, C Chen, S Fan, Y Chong, R Li, C Ge, C Chen, J Yin*. Bactericidal Effects of Silver Nanoparticles on Lactobacilli and the Underlying Mechanism. ACS Applied Materials & Interfaces, 2018, 10, 8443-8450.    IF: 8.097

    5.M Li,# M Gu,#X Tian,# B Xiao, S Lu, W Zhu, L Yu,* Z Shang*. Hydroxylated-Graphene Quantum Dots induce DNA Damage and Disrupt Microtubule Structure in Human Esophageal Epithelial Cells. Toxicological Sciences, 2018, doi.org/10.1093/toxsci/kfy090.     IF: 4.181

    6.Y Deng,#X Tian,# S Lu, M Xie, Hai Hu, R Zhang, Feng Lv, L Cheng, H Gu, Y Zhao,* Yue Pan*.Fabrication of Multifoliate PtRu Bimetallic Nanocomplexes for Computed Tomography Imaging and Enhanced Synergistic Thermoradiotherapy. ACS Applied Materials & Interfaces, 2018, 10, 31106−31113.     IF: 8.097

    7.Y Pan,# P Xue,# S Liu,# L Zhang, Q Guan, J Zhu, X Tian*. Metal-Based Hybrid Nanoparticles as Radiosensitizers in Cancer Therapy. Colloid and Interface Science Communications, 2018, 23, 45-51.

    8.X Tian,# Z Yang,# G Duan,# A Wu, Z Gu, L Zhang, C Chen, Z Chai, C Ge,* R Zhou*. Graphene Oxide Nanosheets Retard Cellular Migration via Disruption of Actin Cytoskeleton. Small, 2017, 13, 1602133-1602142.      IF: 9.598

    9.X Tian,# L Zhang,# M Yang, L Bai, Y Dai, Z Yu, Y Pan*. Functional Magnetic Hybrid Nanomaterials for Biomedical Diagnosis and Treatment. WIREs Nanomedicine Nanobiotechnology, 2017, e1476. doi: 10.1002/wnan.1476. IF: 6.350

    10.X Liu, X Zhang, M Zhu, G Lin, J Liu, Z Zhou, X Tian,* Y Pan*. PEGylated Au@Pt Nanodendrites as Novel Theranostic Agents for Computed Tomography Imaging and Photothermal/Radiation Synergistic Therapy. ACS Applied Materials & Interfaces, 2017, 9, 279-285.     IF: 8.097

    11.X Tian,# B Xiao,# A Wu, L Yu, J Zhou, Y Wang, N Wang, H Guan,* Z Shang*. Hydroxylated-Graphene Quantum Dots Induce Cells Senescence in Both p53-Dependent and -Independent Manner. Toxicology Research, 2016, 5, 1639-1648.   IF: 1.890

    12.C Chen, S Fan,* Y Chong, J Zheng, P Fu, X Tian,* X Jiang, W Wamer, J Yin*. Platinum Nanoparticles Inhibit Antioxidant Effects of Vitamin C via Ascorbate Oxidase-Mimetic Activity. Journal of Materials Chemistry B, 2016, 4, 7895-7901.      IF: 4.776

    13.Y Li,# Y Deng,#X Tian,# H Ke,* M Guo, A Zhu, T Yang, Z Guo, Z Ge, X Yang, H Chen*. Multipronged Design of Light-Triggered Nanoparticles to Overcome Cisplatin Resistance for Efficient Ablation of Resistant Tumor. ACS Nano, 2015, 9, 9626-9637.     IF: 13.709

    14.X Cheng,#X Tian,# A Wu, J Li, J Tian, Y Chong, Z Chai, Y Zhao, C Chen, C Ge*. Protein Corona Influences Cellular Uptake of Gold Nanoparticles by Phagocytic and Nonphagocytic Cells in a Size-Dependent Manner. ACS Applied Materials & Interfaces, 2015, 7, 20568-20575.     IF: 8.097

    15.X Tian, M Zhu, L Du, J Wang, Z Fan, J Liu, Y Zhao, G Nie*. Intrauterine Inflammation Increases Materno-Fetal Transfer of Gold Nanoparticles in a Size-Dependent Manner in Murine Pregnancy. Small, 2013, 9, 2432-2439. IF: 9.598

    16.X Tian,# M Zhu,# Y Tian, R Grant, Y Zhao, G Nie*. A Membrane Vesicle-Based Dual Vaccine against Melanoma and Lewis Lung Carcinoma. Biomaterials, 2012, 33, 6147-6154.     IF: 8.806

    17.M Zhu,#X Tian,# X Song, Y Tian, Y Zhao,* G Nie*. Nanoparticle-Induced Exosomes Target Antigen-Presenting Cells to Initiate Th1-Type Immune Activation. Small, 2012, 8, 404-412.     IF: 9.598

    18.X Tian, M Zhu, G Nie*. How Can Nanotechnology Help Membrane Vesicle-Based Cancer Immunotherapy Development? Human Vaccines, 2012.DOI:10.4161.     IF: 2.229