受Journal of Materials Chemistry B 编辑邀请，多模态辐射技术研究中心胡亮副教授与深圳大学舒桐副教授以“Stimuli-responsive polymer-based systems for diagnostic applications”为题，综述了刺激响应性聚合物在医学诊断相关领域的最新研究进展（J. Mater. Chem. B, SCI二区, IF=5.344）。本文得到国家自然科学基金(No. 51873137),江苏高校优势学科建设工程项目, 放射医学与辐射防护国重内部协作课题(No. GZN1201801)等大力支持。

摘要：Stimuli-responsive polymers exhibit properties that make them ideal candidates for biosensing and molecular diagnostics. Through rational design of polymer composition combined with new polymer functionalization and synthetic strategies, polymers with myriad responsivities, e.g., responses to temperature, pH, biomolecules, CO2, light, and electricity can be achieved. When these polymers are specifically designed to respond to biomarkers, stimuli-responsive devices/probes, capable of recognizing and transducing analyte signals, can be used to diagnose and treat disease. In this review, we highlight recent state-of-the-art examples of stimuli-responsive polymer-based systems for biosensing and bioimaging.

        Tong Shu,⁺ Liang Hu,⁺ Qiming Shen, Li Jiang, Qiang Zhang* and Michael J. Serpe*, Stimuli-responsive polymer-based systems for diagnostic application. J. Mater. Chem. B, 2020, 8, 7042-7061. Tong Shu,⁺ Liang Hu,⁺ 共一；Qiang Zhang* and Michael J. Serpe* 共通讯。