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胡文涛


 日期:2016-11-25 16:50:39 人气:448 

胡文涛,讲师

电话:0512-65882451   传真:0512-65884380

电子邮箱:wthu@suda.edu.cn
通讯地址:苏州工业园区仁爱路199, 邮编215123

个人简历:

2006年毕业于兰州大学生物系,获理学学士学位。2013年毕业于中国科学院近代物理研究所,获粒子物理与原子核物理专业博士学位。博士期间受国家留学基金委资助赴新泽西医科与牙科大学放射肿瘤系联合培养一年。20137月至20167月于中国科学院近代物理研究所任助理研究员,20168月起加入苏州大学医学部放射医学与防护学院。作为项目负责人主持国际自然科学基金青年基金一项、中国科学院“西部之光”项目一项,作为主要人员参加包括973计划、国家自然科学基金重点项目、国家自然科学基金面上项目、中国科学院先导专项等多个项目。在国内外核心期刊发表文章十余篇。

研究方向:

1. 空间辐射致肿瘤发生的分子机制;

2. 非编码RNA与辐射生物学效应;

3. 空间多种环境因素的复合生物学效应。

科研项目:

1. 中国科学院西部之光项目空间辐射诱导的旁观者效应通过诱导肺部EMT促使肺癌发生Y463040XBB20140101-2016123120万元,主持。

2. 国家自然科学基金青年科学基金项目,RAC2基因辐射诱导表达对黑色素瘤细胞辐射敏感性的影响,1140523520150101-2017123128万元,主持。

3. 国家自然科学基金重点项目,空间辐射与微重力复合作用所诱发的上皮细胞间质转换及其在肿瘤发生中的作用,1033501120140101-20181231360万元,参加。

代表性论著:

1. Yi Yu, Wei Wang, Lei Song, Wentao Hu, Chi Dong, Hailong Pei, Guangming Zhou, Zhongjin Yue. Ecto-5'-nucleotidase expression is associated with the progression of renal cell carcinoma. Oncology Letters. 2015, 9(6): 2485-2494.

2. Shuai Xu, Jufang Wang, Nan Ding, Wentao Hu, Xurui Zhang, Bing Wang, Junrui Hua, Wenjun Wei, Qiyun Zhu. Exosome-mediated microRNA transfer plays a role in radiation-induced bystander effect. RNA Biology. 2015, 12(12): 1355-1363.

3. Wentao Hu, Shuai Xu, Bin Yao, Mei Hong, Xin Wu, Hailong Pei, Lei Chang, Nan Ding, Xiaofei Gao, Caiyong Ye, Jufang Wang, Tom K Hei, Guangming Zhou. miR-663 inhibits radiation-induced bystander effects by targeting TGFB1 in a feedback mode. RNA Biology. 2014, 11(9): 1189-1198.

4. Hailong Pei, Weiqiang Chen, Wentao Hu, Mingyue Zhu, Tingting Liu, Jufang Wang, Guangming Zhou. GANRA-5 protects both cultured cells and mice from various radiation types by functioning as a free radical scavenger. Free Radical Research. 2014, 48(6): 670-678.

5. Xin Wu, Nan Ding, Wentao Hu, Jinpeng He, Shuai Xu, Hailong Pei, Junrui Hua,  Guangming Zhou, Jufang Wang. Down-regulation of BTG1 by miR-454-3p enhances cellular radiosensitivity in renal carcinoma cells. Radiation Oncology. 2014, 9: 179.

6. Xin Wu, Nan Ding, Wentao Hu, Jinpeng He, Lei Chang, Shuai Xu, Hailong Pei, Junrui Hua, Jufang Wang, Guangming Zhou. A microRNA network functioning in the regulation of radiobiological effects. Journal of Radiation Research. 2014, 55(Suppl 1): i57-i58.

7. Nan Ding, Hailong Pei, Wentao Hu, Jinpeng He, He Li, Jufang Wang, Tieshan    Wang, Guangming Zhou. Cancer risk of high-charge and -energy ions and the biological effects of the induced secondary particles in space. Rendiconti Lincei-Scienze Fisiche E Naturali. 2014, 25(Suppl 1): s59-s63.

8. Shuai Xu, Nan Ding, Hailong Pei, Wentao Hu, Wenjun Wei, Xurui Zhang, Guangming Zhou, Jufang Wang. MiR-21 is involved in radiation-induced bystander effects. RNA Biology. 2014, 11(9): 1161-1170.

9. Wentao Hu, Hailong Pei, He Li, et al. Effects of shielding on the induction of 53BP1 foci and micronuclei after Fe ion exposures. Journal of Radiation Research. 2014, 55(1): 10-16.

10. Jufang Wang, Jinpeng He, Fengtao Su, Dan Ding, Wentao Hu, Bin Yao, et al. Repression of ATR pathway by miR-185 enhances radiation-induced apoptosis and proliferation inhibition. Cell Death & Disease. 2013, 4: e699.

11. Caiyong Ye, Xurui Zhang, Jianghua Wan, Lei Chang, Wentao Hu, Zhitong Bing, Sheng Zhang, Junhong Li, Jinpeng He, Jufang Wang, Guangming Zhou. Long-term G2-arrested cells exposed to ionizing radiation undergo cellular senescence via slipping into the G1 phase. Cell Cycle. 2013, 12(9): 1424-1432.

12. Lei Chang, Wentao Hu, Caiyong Ye, Bin Yao, Lei Song, Xin Wu, Nan Ding, Jufang Wang, Guangming Zhou. miR-3928 Activates ATR Pathway by Targeting Dicer. RNA Biology. 2012, 9(10): 1247-1254.


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