ENGLISH
   
 
 
您所在的位置: > 人才培养 > 研究生教育 > 博士生导师

李桢


 日期:2016-4-5 22:36:48 人气:3537 

李桢,特聘教授、博士生导师

电话:0512-65882931     传真:0512-65882931

电子邮箱:zhenli@suda.edu.cn

通讯地址:苏州工业园区仁爱路199, 邮编215123

个人简介:

李桢,苏州大学放射医学与防护学院特聘教授,博士生导师,中组部第十二批“青年千人计划”入选者(2016)、江苏省“双创人才”(2016)、“江苏省第五批特聘教授”入选者(2014)、德国洪堡学者(2006)和澳大利亚Queensland Smart Futures Fellow (2009)。2005年博士毕业于中国科学院化学研究所,之后9年间先后在英国利物浦大学、德国锡根大学、澳大利亚昆士兰大学和澳大利亚卧龙岗大学担任助理研究员、洪堡学者、以及研究员,于2014年到苏州大学放射医学与防护学院工作,开展多模态分子影像在重大疾病精准诊断与精准治疗的相关研究。目前已转让发明专利2项,申请专利6项,撰写英文专著2章,发表SCI论文110余篇(其中40%论文发表在影响因子大于5的国际期刊),论文被引3900余次(单篇引用超过100次的有10篇)。研究成果荣获北京市科学技术一等奖(2014)、苏州市科技三等奖(2015)和华夏医学科技三等奖(2016)。

研究方向:

多模态分子影像(光声成像、荧光成像、核磁共振成像(MRI)、核医学成像(SPECT/CT PET)等)在重大疾病精准诊断与精准治疗方面的研究,具体包括:

1.多模态诊疗一体化分子影像探针的制备、表征和修饰;

2. 多模态分子影像在肿瘤诊断与治疗中的应用;

3. 多模态分子影像在神经疾病诊断与治疗中的应用。

科研项目:

1.        中组部,第十二批青年千人计划,2016年,300万,主持;

2.        国家自然科学基金重大仪器研制项目(81527901):基于超声辐射力的深部脑刺激与神经调控仪器研制2016年,268万元,参与。

3.        江苏省第五批特聘教授:多模态分子影像诊疗探针2014年,100万,主持。

4.        国家自然科学基金面上项目(81471657):基于超小磁性纳米颗粒的多模态分子影像探针2015年,72万元,主持。

20篇代表性论著:(*为通讯作者):

1.        S. H. Zhang, C. X. Sun, J. F. Zeng, G. L. Wang, Y. Wang, Q. Sun,Y. Wu, M. Y. Gao, S. X. Dou, Z. Li*, Ambient Aqueous Synthesis of Ultra-small PEGylated Cu2?xSe Nanoparticles as a Multifunctional Theranostic Agent for Multimodal Imaging Guided Photothermal Therapy of Cancer, Adv. Mater., 2016, 28, 8927-8936.

2.        L. Wen, L. Chen, S. M. Zheng, J. F. Zeng, G. X. Duan, Y. Wang, G. L. Wang, Z. F. Chai, Z. Li*, M. Y. Gao*, Ultrasmall Biocompatible WO3-x Nanodots for Multi-modality Imaging and Combined Therapy of Cancers, Adv. Mater., 2016, 28, 5072-5079.

3.        F. X. Mao, L. Wen, C. Sun, S. Zhang, G. Wang, J. Zeng, Y.Wang, J.M Ma*, M. Y Gao, Z. Li*, Ultrasmall Biocompatible Bi2Se3 Nanodots for Multimodal Imaging-Guided Synergistic Radiophotothermal Therapy against Cancer, ACS Nano, 2016, 10, 11145–11155.

4.        Y. Wang, Y. Y. Wu, Y. J. Liu, J. Shen, L. Lv, L. B. Li, L. C. Yang, J. F. Zeng, Y. Y. Wang, L. S. W. Zhang*, Z. Li*, M.Y. Gao*, Z. F. Chai, BSA-Mediated Synthesis of Bismuth Sulfide Nanotheranostic Agents for Tumor Multimodal Imaging and Thermoradiotherapy, Adv. Funct. Mater., 2016, 26, 5335-5344.

5.        C. X. Sun, L. Wen, J. F. Zeng, Y. Wang, Q. Sun, L. J. Deng, C. J. Zhao*, Z. Li*, One-pot Solventless Preparation of PEGylated Black Phosphorus Nanoparticles for Photoacoustic Imaging and Photothermal Therapy of Cancer, Biomaterials, 2016, 91, 81-89.

6.        J. F. Zeng, M. Cheng, Y. Wang, L. Wen, L. Chen, Z. Li*, *Y. Y. Wu, *M. Y. Gao, Z. F. Chai, pH-Responsive Fe(III)-Gallic-Acid Nanoparticles for In-Vivo Photoacoustic Imaging Guided Photothermal Therapy, Adv. Healthcare Mater, 2016, 5, 772-780.

7.        C. Han, Q. Sun, Z. Li*, S. X. Dou, Thermoelectric enhancement of different kinds of metal chalcogenides, Adv. Energy Mater., 2016, 6, 1600498.

8.        C. Han, Z. Li*, G. Q. Lu, S. X. Dou, Robust scalable synthesis of surfactant-free thermoelectric metal chalcogenide nanostructures, Nano Energy 2015, 15193-204.

9.        Y. Bai, C. Han, X. Q. Chen, H. Yu, X. Zong, Z. Li*, L. Z. Wang*, Boosting the efficiency of quantum dot sensitized solar cells up to 7.11% through simultaneous engineering of photocathode and photoanode, Nano Energy 2015, 13, 609-619.

10.    C. Han, Q. Sun, Z. X. Cheng., J. L. Wang, Z. Li*, G. Q. Lu, S. X. Dou, Ambient Scalable Synthesis of Surfactant-free Thermoelectric CuAgSe Nanoparticles with Reversible Metallic-n-p Conduc-tivity Transition, J. Am. Chem. Soc., 2014, 136, 17626-17633.

11.    Q. Sun, Z. Li*, D. J. Searles*, Y. Chen, G. Q. (Max) Lu, A. J. Du*, Charge-Controlled Switchable CO2 Capture on Boron Nitride Nanomaterials, J. Am. Chem. Soc., 2013, 135, 8246-8253.

12.    Z. Li*, S. X. Wang, Q. Sun, H. L. Zhao, H. Lei, M. B. Lan, Z. X. Cheng, X. L. Wang, S. X. Dou, G. Q. Lu*, Ultrasmall Manganese Ferrite Nanoparticles as Positive Contrast Agent for Magnetic Resonance Imaging, Adv. Healthcare Mater., 2013, 2, 958-964.

13.    Z. Li*, P. W. Yi, Q. Sun, H. Lei, H. L. Zhao, Z. H. Zhu, S. C. Smith, M. B. Lan, G. Q. Lu*, Ultrasmall Water-soluble and Biocompatible Magnetic Iron Oxide Nanoparticles as Positive and Negative Dual Contrast Agents, Adv. Funct. Mater., 2012, 22, 2387-2393.

14.    Z. Li*, L. N. Cheng, Q. Sun, Z. H. Zhu, M. J. Riley, M. Aljada, Z. X. Cheng, X. L. Wang, S. Z. Qiao, S. C. Smith, G. Q. Lu*, Diluted Magnetic Semiconductor Nanowires Prepared by Solution-Liquid-Solid Method, Angew. Chem. Int. Ed., 2010, 49, 2777-2781.

15.    Z. Li*, O. Kurtulus, N. Fu, A. Myalitsin, Z. Wang, A. Kornowski, U. Pietsch, A. Mews*, Controlled-Synthesis of CdSe Nanowires by Solution-Liquid-Solid Method, Adv. Funct. Mater., 2009, 19, 3650-3661.

16.    Z. Li, B. Tan, M. Allix, A. I. Cooper*, M. J. Rosseinsky*, Direct Coprecipitation Route to Monodispersed Dual-Functionalized Magnetic Iron Oxide Nanocrystals without Size Selection, Small, 2008, 4, 231-239.

17.    Z. Li*, A. Kornowski, A. Myalitsin, A. Mews*, Formation and Function of Bismuth Nanocatalysts for the Solution-Liquid-Solid Synthesis of CdSe Nanowires, Small, 2008, 4, 1698-1702.

18.    Z. Li, L. Wei, M. Y. Gao*, H. Lei*, One-pot Reaction to Synthesize Biocompatible Magnetite Nanoparticles, Adv. Mater., 2005, 17, 1001-1005. (286 citations)

19.    Z. Li, Q. Sun, M. Y. Gao*, Preparation of Water-soluble Magnetite Nanocrystals by Refluxing Ferric Hydrated Salts in 2-Pyrrolidone: Mechanism Leading to Fe3O4, Angew. Chem. Int. Ed., 2005, 44, 123-126. (180 citations)

20.    Z. Li, H. Chen, H. B. Bao, M. Y. Gao*, One-Pot Reaction to Synthesize Water-Soluble Magnetite Nanocrystals, Chem. Mater., 2004, 16, 1391-1393. (257 citations)

专利:

1.             一种高结晶度的水分散性磁性纳米微粒的制备方法, 发明专利: 03136275.3 (已转让).

2.             一种制备具有生物相容性的磁性纳米微粒的方法, 发明专利: 03136273.7(已转让).

3.             Z. Li, X. Q. Chen, S. X. Dou, ‘Method of Preparing Metal Chalcogenide Nanomaterials’, International Patent Application No. PCT/CN2015/080452.

4.             Z. Li, C. Han, S. X. Dou, ‘Aqueous-based Method of Preparing Metal Chalcogenide Nanomaterials’, International Patent Application No. PCT/CN2015/080464.

教学:

新生研讨课:《纳米技术与健康》。

招生信息:

招收具有化学、材料学、影像学、生物学、放射医学背景的硕士研究生,博士生,博士后,以及科研助理。同时也欢迎化学专业及医学类本科生来参加带薪科研和完成毕业论文

上一篇: 华道本