王畅，教授、硕士生导师
电子邮箱：wangchang[AT]suda.edu.cn
通讯地址：苏州工业园区仁爱路199号, 邮编215123
2006年3月于中国科学院大连化学物理研究所获得理学博士学位。2015.6-2016.6在美国加州大学戴维斯分校做访问学者，进行氧化脂类（oxylipin）的研究。2006年4月起至今于苏州大学工作，从事辐射损伤标志物以及临床疾病早期诊断以及药效评估的研究。先后主持国家自然基金项目2项，江苏省高校自然科学研究项目1项，参与国家自然科学基金联合基金重点支持项目1项。参与撰写研究专著两部。
学习简历：
1995-1999 年 陕西师范大学化学系本科
1999-2002 年 陕西师范大学化学系硕士（导师：章竹君教授）
2002-2006 年 中国科学院大连化学物理研究所（导师：许国旺研究员）
研究方向：
基于代谢组学和脂质组学的辐射损伤生物标志物研究
临床疾病早期诊断以及药效评估的研究
代表性论文：
1. Early metabolic characterization of brain tissues after whole body radiation based on gas chromatography-mass spectrometry in a rat model
Xueting Yao， Chao Xu，Yurong Cao， Lin Lin，Hanxu Wu，Chang Wang*
Biomed Chromatogr.2019, 33 (3): e4448.
2. Early metabolic characterization of brain tissues after whole body radiation based on gas chromatography-mass spectrometry in a rat model
Xueting Yao， Chao Xu，Yurong Cao， Lin Lin，Hanxu Wu，Chang Wang*
Biomed Chromatogr. 2018, doi: 10.1002/bmc.4448.
3. Monitoring tyrosine kinase inhibitor therapeutic responses with a panel of metabolic biomarkers in chronic myeloid leukemia patients
Bingyu Yang, Chang Wang#, Yiyu Xie, Liangjing Xu, Xiaojin Wu, Depei Wu
Cancer Sci. 2018, Cancer Sci, 109(3): 777-784.
4. Prediction of acute GVHD and relapse by metabolic biomarkers after allogeneic hematopoietic stem cell transplantation
Wu X, Xie Y, Wang C#, Han Y, Bao X, Ma S, Yilmaz A, Yang B, Ji Y, Xu J, Liu H, Chen S, Zhang J, Yu J, Wu D.
JCI Insight, 2018,3(9). pii: 99672. doi: 10.1172/jci.insight.99672
5. Urinary Metabolic Signatures and Early Triage of Acute Radiation Exposure in Rat Model
Mingxiao Zhao, Kim KT Lau, Xian Zhou, Jianfang Wu, Jun Yang, Chang Wang*
Molecular BioSystems, 2017, 13(4):756-766.
6. Assessment of early triage for acute radiation injury in rat model based on urinary amino acid target analysis
Yuanyuan Zhang, Xian Zhou, Chao Li, Jianfang Wu, John E. Kuo, Chang Wang*
Molecular BioSystems, 2014, 10(6): 1441-1449.
7. Quantification of amino acids in rat urine by solid phase extraction and liquid chromatography/electrospray tandem mass spectrometry: application to radiation injury rat model
Xinxing Tang, Yuan Gu, Jihua Nie, Saijun Fan, Chang Wang*
Journal of Liquid Chromatography & Related Technologies, 2014, 37(7): 951-973.
8. Estimation value of plasma amino acid target analysis to the acute radiation injury early triage in the rat model
Xinxing Tang, Mingchen Zheng,Yuanyuan Zhang, Saijun Fan, Chang Wang*
Metabolomics, 2013 (9): 853-863.
9. Plasma phospholipid metabolic profiling and biomarkers of rats following radiation exposure based on liquid chromatography–mass spectrometry technique
Chang Wang*, Yun Yang, Jihua Nie
Biomed.Chromatogr，2009, 23: 1079-1085.
10. Plasma Phospholipid Metabolic Profiling and Biomarkers of Type 2 Diabetes Mellitus Based on High Performance Liquid Chromatography/Electrospray Mass Spectrometry and Multivariate Statistical Analysis
Chang Wang*, Hongwei Kong, Yufeng Guan, Jun Yang, Jianren Gu, Shengli Yang, Guowang Xu
Anal. Chem., 2005，77：4108-4116