Name: Jingzhou Chen
Academic Title: Lecturer
Email: jingzhouchen@suda.edu.cn
Address: 402-2303, North District of Dushuhu Campus
Contact Phone: +86 175 5987 4259
I. Educational and Professional Experience
1. Educational Background：
2019.09-2024.06 Zhejiang University, Ph.D. in Biochemistry and Molecular Biology
2015.09-2019.06 Northeast Forestry University, B.S. in Animal Science
2. Professional Experience：
2026.07 to date School of Radiation Medicine and Protection, Soochow University, Lecturer 2024.09-2026.06 School of Public Health, Zhejiang University, Postdoctoral research scientist
II. Research Focus
1. Biological effects and mechanisms of space HZE particles
2. Biological mechanism underlying FLASH radiotherapy
3. Novel strategies for radiation protection
III. Project/Honor/Award
1. Discovery of novel intestinal antimicrobial peptides and their roles and mechanisms in maintaining gut microbiota homeostasis. NSFC U21A20202, ￥2.63M, 2022.01-2025.12, Ongoing, co-PI.
2. Mechanisms of Gut Homeostasis Maintenance. ZJNSF, LR24H030001, ￥0.8M, 2024.01-2026.12, Ongoing, co-PI.
3. Excellent Poster Presentation Award, 2024, National Academic Conference, Chinese Society for Biochemistry and Molecular Biology.
4. Distinguished Oral Presentation Award, 2024, Annual Conference, Zhejiang Society of Biochemistry and Molecular Biology.
IV. Academic Part-time Roles & Student Guidance Outcomes
Not applicable
V. Recent Five-Year Representative Research Outcomes
1. Jingzhou Chen; Xiaoliang Shi; Xinyi Zhou; Ju Huang; Linghao Xia; Zhen Hu; Jiaji Gu; Xiaole Sheng; Xiaolong Ge; Xudong Fu; Qian Xiao; Wei Zhou; Rongpan Bai; Zhengping Xu; Jinghao Sheng. G9a-mediated H3K9me2 orchestrates intestinal epithelial regeneration through epigenetic silencing of cell cycle-related genes. Nature Communications. 2026 17(1): 1-15.
2. Xiaoliang Shi; Jingzhou Chen; Rongpan Bai; Hao Bai; Yaxin Liu; Zhengrong Yao; Weiwei Chu; Xin Xu; Ning Shen; Yuanhui Mao; Guo-fu Hu; Mingjuan Jin; Kun Chen; Jinghao Sheng; Zhengping Xu. Ribonuclease 5/Angiogenin suppresses intestinal tumor initiation by maintaining crypt homeostasis. Cancer Res. 2026 Jun 1;86(11):2643-2659.
3. Xinxin Chai; Jingzhou Chen; Yuanyuan Zhao; Weiwei Chu; Jianuo Zhou; Yurong Zhao; Zhen Hu; Jiayi Zhu; Yi Zhu; Zhengping Xu; Jinghao Sheng. G9a epigenetically suppresses CXCL10 expression and inhibits anti-tumor immunity in hepatocellular carcinoma. International Journal of Cancer. 2025 158(7): 1960-1974.
4. Zhao Yurong; Chai Xinxin; Peng Junxuan; Zhu Yi; Dong Rong; He Junwei; Xia Linghao; LiuSishuo; Chen Jingzhou; Xu Zhengping; Luo Chi; Sheng Jinghao. Proline exacerbates hepatic gluconeogenesis via paraspeckle-dependent mRNA retention. Nature Metabolism. 2025 7(2): 367-382.