姓 名：胡文涛
职称/职务：副教授
电子邮箱：wthu@suda.edu.cn
办公地址：独墅湖北区医学楼402-2222
联系电话：+86 512 65882451
一、学习工作经历
1、学历背景：
2011.10-2012.10 罗格斯大学，放射肿瘤学系，联合培养博士
2007.09-2013.07 中国科学院大学，近代物理研究所，理学博士
2、工作经历：
2019.07-至今苏州大学，放射医学与防护学院，副教授
2016.08-2019.06 苏州大学，放射医学与防护学院，讲师
2013.07-2016.07 中国科学院近代物理研究所，助理研究员
二、研究方向
1、粒子辐射生物学效应及机理
2、空间辐射致肿瘤发生的分子机制
3、辐射生物学效应的表观遗传学调控
三、项目、荣誉和奖励
1、国家自然科学基金-面上项目， TGF-β依赖性的cGAS-STING通路在脑胶质瘤质子FLASH放疗中的调控机制研究，12475350，53万元，2025.01-2028.12
2、国家自然科学基金-重大项目子课题，航天极端环境下机体不同组织器官间的交互调控作用研究，82192882，74万元，2022.01-2026.12
3、国家自然科学基金-面上项目，空间辐射与微重力通过β-arrestin1-FN1-YAP通路协同诱导肿瘤发生的机理研究，32071243，58万元，2021.01-2024.12
4、国家自然科学基金-青年科学基金项目，RAC2基因辐射诱导表达对黑色素瘤细胞辐射敏感性的影响，11405235，28万元，2015.01-2017.12
5、中国科学院“西部之光”项目，空间辐射诱导的旁观者效应通过诱导肺部EMT促使肺癌发生，Y463040XBB，20万元，2014.01-2016.12
四、学术兼职、指导学生成果等
1、苏州大学创新创业教育先进个人，2025
3、中国核学会核应急分会理事，2020-2024，2024-2028
五、近五年代表性研究成果
1. Yunan Ding, Ying Xu, Xiaofei Wang, Miaomiao Zhang, Qi Zeng, Congchong Yan*, Guangming Zhou*, Wentao Hu*. Microgravity alleviates low-dose radiation-induced non-targeted carcinogenic effects. NPJ Microgravity. 2025, 11(1): 26.
2. Shanghai Liu, Xiangyang He, Siqi Liang, Anqing Wu*, Lu Liu*, Wentao Hu*. Carbon ion irradiation mobilizes antitumor immunity: from concept to the clinic. Radiation Oncology. 2025, 20(1): 85.
3. Hao Huang#, Ying Xu#, Zi Guo, Miaomiao Zhang, Wanshi Li, Yidan Song, Wentao Hu*, Tom K. Hei*, Guangming Zhou*. Irradiation-responsive PRDM10-DT modulates the angiogenic response in human NSCLC cells in an SP1-dependent manner via the miR-663a/TGF-β1 axis. Journal of Translational Medicine. 2025, 23(1): 235.
4. Ping Wang#, Jiming Xu#, Weijing You#, Jie Li, Jing Yu, Fei Jiang, Zengli Zhang, Wentao Hu*, Bingyan Li*. CYP24A1 binding to FUS maintains tumor properties by regulating the miR-200c/ZEB1/EMT axis. Cancer Science. 2025, 116(4): 910-922.
5. Kuan Lu#, Chenxia Zhou#, Jiaming Ren#, Jialu Ni, Weisen Yang, Yeqing Wang, Dan Jin, Jianjun Qian, Yaqun Zhu, Dai Shi*, Wentao Hu*, Liang Xu*. Preliminary study on the correlation between thyroid magnetic resonance parameters and radiation dose after radiotherapy for nasopharyngeal carcinoma. Frontiers in Public Health. 2025, 12: 1526147.
6. Wenying Yan#, Wentao Hu#, Yidan Song#, Xingyi Liu, Ziyun Zhou, Wanshi Li, Zhifei Cao, Weiwei Pei*, Guangming Zhou*, Guang Hu*. Differential network analysis reveals the key role of the ECM-receptor pathway in α-particle-induced malignant transformation. Molecular Therapy-Nucleic Acids. 2024, 12(9): 102260.
7. Yunan Ding, Guangming Zhou*, Wentao Hu*. Epigenetic regulation of TGF-β pathway and its role in radiation response. International Journal of Radiation Biology. 2024, 100(6): 834-848.
8. Haoyi Tang#, Hao Huang#, Zi Guo, Haitong Huang, Zihe Niu, Yi Ji, Yuyang Zhang, Huahui Bian*, Wentao Hu*. Heavy ion-responsive lncRNA EBLN3P functions in the radiosensitization of non-small cell lung cancer cells mediated by TNPO1. Cancers. 2023, 15(2): 511.
9. Zi Guo, Guangming Zhou*, Wentao Hu*. Carcinogenesis induced by space radiation: A systematic review. Neoplasia. 2022, 32: 100828.
10. Hao Huang#, Guotao Yuan#, Ying Xu, Yuan Gao, Qiulian Mao, Yin Zhang, Lu Bai, Weijie Li, Anqing Wu, Wentao Hu*, Yue Pan*, Guangming Zhou*. Photoacoustic and magnetic resonance imaging-based gene and photothermal therapy using mesoporous nanoagents. Bioactive Materials. 2022, 9(2022): 157-167.