姓名：叶才勇
职称/职务：副研究员
办公地址：独墅湖北区医学楼402-2308
一、学习工作经历
1、教育经历：
2008.09-2013.07, 中国科学院大学（近代物理研究所）, 粒子物理与原子核物理, 理学博士
2004.09-2008.07, 云南大学, 生物科学, 理学学士
2、工作经历：
2020.07-至今, 苏州大学, 苏州医学院放射医学与防护学院, 副研究员
2018.09-2020.06, Rutgers University, Rutgers Cancer Institute of New Jersey, 助理研究员
2013.08-2018.08, Rutgers University, Rutgers Cancer Institute of New Jersey, 博士后
二、研究方向
1、辐射生物效应
2、DNA复制和损伤修复
三、代表性研究成果
1.Luo Chenyu#, Liang Haisheng#, Ji Mintao#, Ye Caiyong#, Lin Yiping, Guo Yuhan, Zhang Zhisen, Shu Yinyin, Jin Xiaoni, Lu Shuangshuang, Lu Wanling, Dang Yazheng, Zhang Hong, Li Bingyan, Zhou Guangming, Zhang Zengli, Chang Lei. Autophagy induced by mechanical stress sensitizes cells to ferroptosis by NCOA4-FTH1 axis. Autophagy, 202521(6):1263-1282.
2.Kang, Zhihua, Fu, Pan, Alcivar, Allen L., Fu, Haiqing, Redon, Christophe, Foo, Tzeh Keong, Zuo, Yamei, Ye, Caiyong, Baxley, Ryan, Madireddy, Advaitha, Buisson, Remi, Bielinsky, Anja-Katrin, Zou, Lee, Shen, Zhiyuan, Aladjem, Mirit, I, Xia, Bing. BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage. Nat Commun, 2021, 12(1): 5966-5977.
3.Ping Wang, Jin Nie, Jiafu Li, Caiyong Ye, Jianwu Chen, Zengli Zhang, Bingyan Li. VDRA downregulate β-catenin/Smad3 and DNA damage and repair associated with improved prognosis in ccRCC patients. Int J Biol Macromol. 2024, 263(Pt 2):130405
4.Huimei Lu, Caiyong Ye, Jingmei Liu, Arnold B. Rabson, Michael Verzi, Subhajyoti Be, Zhiyuan Shen. Requirement of Bccip for the Regeneration of Intestinal Progenitors. Am J Pathol, 2021, 191(1): 66-78.
5.Huimei Lu, Caiyong Ye, Xing Feng, Jingmei Liu, Mantu Bhaumik, Bing Xia, Chen Liu, Zhiyuan Shen. Spontaneous Development of Hepatocellular Carcinoma and B-Cell Lymphoma in Mosaic and Heterozygous Brca2 and Cdkn1a Interacting Protein Knockout Mice. Am J Pathol, 2020, 190(6):1175-1187.
6.Caiyong Ye, Bochao Liu, Huimei Lu, Jingmei Liu, Arnold B. Rabson, Estela Jacinto, Dimitri G. Pestov, Zhiyuan Shen. BCCIP is required for nucleolar recruitment of eIF6 and 12S pre-rRNA production during 60S ribosome biogenesis. Nucleic Acids Res, 2020, 48(22): 12817-12832.
7.Caiyong Ye, Xurui Zhang, Jianghua Wang, Lei Chang, Wentao Hu, Zhitong Bing, Sheng Zhang, Junhong Li, Jinpeng He, Jufang Wang, Guangming Zhou. Radiation-induced cellular senescence results from a slippage of long-term G2 arrested cells into G1 phase. Cell Cycle, 2013, 12(9):1424-1432.