姬丹阳，副教授、硕士生导师

办公室：401-1117

电子邮箱：jdy@suda.edu.cn
通讯地址：苏州工业园区仁爱路199号,邮编215123


个人简历：

姬丹阳，2023年于香港城市大学获得博士学位，2024年加入苏州大学放射医学与防护学院，任青年特聘教授。主要从事功能核酸分析和核酸药物开发等研究方向。在Acc. Chem. Res., Nucleic Acids Res., J. Am. Chem. Soc., Angew. Chem. Int. Ed.等国际权威期刊发表SCI论文20余篇。授权美国发明专利3项，中国发明专利1项。主持国家级青年人才计划，江苏省自然科学基金青年基金，江苏省高等学校基础科学研究面上项目，苏州市科技攻关计划，苏州市基础研究项目子课题，苏州大学科研启动基金。曾作为香港青年学者代表参加第71届德国林道诺贝尔奖获得者大会（全香港共5人）。


研究方向：

  1. 核酸适配体的筛选，修饰和应用

  2. G-四链体

  3. 靶向放射性药物开发


代表性论著：

  1. Ji, D., Zhang, K., Yarshova, M., Kwok, C. K. L-RNA Aptamer-Based Tools for G-Quadruplex Structure: Identification, Characterization, and Application.Acc. Chem. Res.,2025, 58 (21), 3247-3258.

  2. Ji, D., Wang, B., Lo, K. W., Tsang, C. M., & Kwok, C. K. Pre-Defined Stem-Loop Structure Library for the Discovery of L‐RNA Aptamers that Target RNA G‐Quadruplexes.Angew.Chem.Int.Ed., 2025,64(5), e202417247. (IF: 16.1)

  3. Ji, D., Yuan, J. H., Chen, S. B., Tan, J. H., Kwok, C. K. Selective targeting of parallel G-quadruplex structure using L-RNA aptamer.Nucleic Acids Res.,2023,51(21), 11439-11452. (IF:16.7)

  4. Ji, D., Feng, H., Liew, S. W., Kwok, C. K. Modified nucleic acid aptamers: development, characterization, and biological applications.Trends Biotechnol.,2023,41(11), 1360-1384.(IF: 14.3)

  5. Guo, W†.;Ji, D†.; Kinghorn, A. B.; Chen, F.; Pan, Y.; Li, X.; Li, Q.; Huck, W. T. S.; Kwok, C. K.; Shum, H. C. Tuning material states and functionalities of G-quadruplex modulated RNA-peptide condensates.J. Am. Chem. Soc.,2023,145(4), 2375-2385.(Co-first author) (IF: 14.5)

  6. Ji, D.; Lyu, K.; Zhao, H.; Kwok, C. K. Circular L-RNA aptamer promotes target recognition and controls gene activity.Nucleic Acids Res.,2021,49(13), 7280-7291.(IF: 16.7)

  7. Ji, D.; Juhas, M.; Tsang, C. M.; Kwok, C. K.; Li, Y.; Zhang, Y. Discovery of G-quadruplex-forming sequences in SARS-CoV-2.Brief. Bioinformatics,2021,22(2), 1150-1160.(IF: 6.8)

  8. Ji, D.; Li, Z.; Kwok, C. K. Rational design and development of a universal baby spinach-based sensing platform for the detection of biomolecules.2019,Analyst,144(24), 7173-7177.(IF: 3.6)

  9. Umar, MI†.;Ji, D†.; Chan, CY†.; Kwok CK., G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications.Molecules2019,24, 2416.(co-first author) ( IF: 4.2)

  10. Ji, D.; Mou, X.; Kwok, C. K., Label-free and ratiometric detection of microRNA based on target-induced catalytic hairpin assembly and two fluorescent dyes.Anal. Methods2019,11(37), 4808-4813. (IF: 2.7)  

  11. Ji, D.; Du, Y.; Meng, H.; Ge, J.; Zhang, L.; Huang, Z.; Hu, Y.; Li, Z., A novel colorimetric strategy for sensitive and rapid sensing of ascorbic acid using cobalt oxyhydroxide nanoflakes and 3,3´,5,5´-tetramethylbenzidine. Sens. Actuators B: Chem.2018,256, 512-519.(IF: 8.0)

  12. Ji, D.; Meng, H.; Ge, J.; Zhang, L.; Wang, H.; Bai, D.; Li, J.; Qu, L.; Li, Z., Ultrasensitive fluorometric glutathione assay based on a conformational switch of a G-quadruplex mediated by silver(I).Microchim. Acta2017,184, 3325-3332.(IF: 5.4)

  13. Ji, D.; Wang, H.; Ge, J.; Zhang, L.; Li, J.; Bai, D.; Li, Z., Label-free and rapid  detection of ATP based on structure switching of aptamers.Anal. Biochem.2017,526, 22-28.(IF: 2.6)